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Metabolism of α-methyltyrosine in man: relationship to its potency as an inhibitor of catecholamine biosynthesis

The metabolic fate of the tyrosine hydroxylase inhibitor, α-methyl-para-tyrosine (α-MPT), was studied after oral administration of single and multiple doses to patients with pheochromocytoma and essential hypertension. No major urinary excretion product was found other than the drug itself, which ac...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Engelman, Karl, Jéquier, Eric, Udenfriend, Sidney, Sjoerdsma, Albert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1968
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5637144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105753
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