Metabolism of α-methyltyrosine in man: relationship to its potency as an inhibitor of catecholamine biosynthesis

The metabolic fate of the tyrosine hydroxylase inhibitor, α-methyl-para-tyrosine (α-MPT), was studied after oral administration of single and multiple doses to patients with pheochromocytoma and essential hypertension. No major urinary excretion product was found other than the drug itself, which ac...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Engelman, Karl, Jéquier, Eric, Udenfriend, Sidney, Sjoerdsma, Albert
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1968
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297203/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5637144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105753
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