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Metabolism of α-methyltyrosine in man: relationship to its potency as an inhibitor of catecholamine biosynthesis

The metabolic fate of the tyrosine hydroxylase inhibitor, α-methyl-para-tyrosine (α-MPT), was studied after oral administration of single and multiple doses to patients with pheochromocytoma and essential hypertension. No major urinary excretion product was found other than the drug itself, which ac...

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Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Engelman, Karl, Jéquier, Eric, Udenfriend, Sidney, Sjoerdsma, Albert
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 1968
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5637144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI105753
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