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SeqEM: an adaptive genotype-calling approach for next-generation sequencing studies
Motivation: Next-generation sequencing presents several statistical challenges, with one of the most fundamental being determining an individual's genotype from multiple aligned short read sequences at a position. Some simple approaches for genotype calling apply fixed filters, such as calling...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2971572/ https://ncbi.nlm.nih.gov/pubmed/20861027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq526 |
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