Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns

Rationale: Immunogenicity of new tuberculosis (TB) vaccines is commonly assessed by measuring the frequency and cytokine expression profile of T cells. Objectives: We tested whether this outcome correlates with protection against childhood TB disease after newborn vaccination with bacillus Calmette-...

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Bibliografiska uppgifter
Huvudupphovsmän: Kagina, Benjamin M. N., Abel, Brian, Scriba, Thomas J., Hughes, Elizabeth J., Keyser, Alana, Soares, Andreia, Gamieldien, Hoyam, Sidibana, Mzwandile, Hatherill, Mark, Gelderbloem, Sebastian, Mahomed, Hassan, Hawkridge, Anthony, Hussey, Gregory, Kaplan, Gilla, Hanekom, Willem A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2010
Ämnen:
E. Tuberculosis and Mycobacterial Disease
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970848/
https://ncbi.nlm.nih.gov/pubmed/20558627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201003-0334OC
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