Reduced miR-146a Increases Prostaglandin E(2) in Chronic Obstructive Pulmonary Disease Fibroblasts

Rationale: Persistent inflammation plays a major role in chronic obstructive pulmonary disease (COPD) pathogenesis, but its mechanisms are incompletely defined. Overproduction of the inflammatory mediator prostaglandin (PG) E(2) by COPD fibroblasts contributes to reduced repair function. Objectives:...

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Detalhes bibliográficos
Main Authors: Sato, Tadashi, Liu, Xiangde, Nelson, Amy, Nakanishi, Masanori, Kanaji, Nobuhiro, Wang, Xingqi, Kim, Miok, Li, Yingji, Sun, Jianhong, Michalski, Joel, Patil, Amol, Basma, Hesham, Holz, Olaf, Magnussen, Helgo, Rennard, Stephen I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
A. Chronic Obstructive Pulmonary Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970844/
https://ncbi.nlm.nih.gov/pubmed/20522791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201001-0055OC
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