Interleukin-4 induces differentiation of human embryonic stem cells into “fibrogenic” fibroblast-like cells

BACKGROUND: Fibroblast heterogeneity is recognized and fibroblasts from diseased tissues, including asthma, have functional phenotypes that differ from normal. However, progenitor progeny relationships and the factors that control fibroblast differentiation are poorly defined. OBJECTIVE: To determin...

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Huvudupphovsmän: Sato, Tadashi, Liu, Xiangde, Basma, Hesham, Togo, Shinsaku, Sugiura, Hisatoshi, Nelson, Amy, Nakanishi, Masanori, Kanaji, Nobuhiro, Wang, Xingqi, Kim, Miok, Li, Yingji, Michalski, Joel, Farid, Maha, Sharp, John G., Rennard, Stephen I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105203/
https://ncbi.nlm.nih.gov/pubmed/21388667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.01.049
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