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Interleukin-4 induces differentiation of human embryonic stem cells into “fibrogenic” fibroblast-like cells

BACKGROUND: Fibroblast heterogeneity is recognized and fibroblasts from diseased tissues, including asthma, have functional phenotypes that differ from normal. However, progenitor progeny relationships and the factors that control fibroblast differentiation are poorly defined. OBJECTIVE: To determin...

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Detalhes bibliográficos
Main Authors: Sato, Tadashi, Liu, Xiangde, Basma, Hesham, Togo, Shinsaku, Sugiura, Hisatoshi, Nelson, Amy, Nakanishi, Masanori, Kanaji, Nobuhiro, Wang, Xingqi, Kim, Miok, Li, Yingji, Michalski, Joel, Farid, Maha, Sharp, John G., Rennard, Stephen I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105203/
https://ncbi.nlm.nih.gov/pubmed/21388667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.01.049
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