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β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

Alzheimer's disease (AD) is the most common dementia-causing disorder in the elderly, which may relate to multiple risk factors and is pathologically featured by cerebral hypometabolism, paravascular β-amyloid (Aβ) plaques, neuritic dystrophy and intra-neuronal aggregation of phosphorylated-tau...

詳細記述

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書誌詳細
主要な著者: Cai, Yan, Xiong, Kun, Zhang, Xue-Mei, Cai, Huaibin, Luo, Xue-Gang, Feng, Jia-Chun, Clough, Richard W., Struble, Robert G., Patrylo, Peter R., Chu, Yaping, Kordower, Jeffrey H., Yan, Xiao-Xin
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970759/
https://ncbi.nlm.nih.gov/pubmed/20726888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2010.07376.x
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