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CD4+ T cell help in the tumor milieu is required for recruitment and cytolytic function of CD8+ T lymphocytes
CD4 help for CD8(+) T lymphocytes prevents tolerance and promotes the survival of effector and memory CD8(+) T cells. Here we describe additional helper functions that require CD4 T cells within the tumor environment. CD8(+) T cell recruitment, proliferation, and effector function within the tumor w...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970736/ https://ncbi.nlm.nih.gov/pubmed/20940398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1322 |
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