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The adaptor protein CIKS/Act1 is necessary to induce collagen-induced arthritis pathology and it contributes to collagen-specific antibody production
OBJECTIVE: CIKS/Act1 is an adaptor molecule necessary for signaling by members of the IL-17 cytokine family. Here we aim to determine whether this adaptor is required for collagen-induced arthritis (CIA). If required, CIKS-mediated signaling could be a potential target for therapeutic intervention i...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970656/ https://ncbi.nlm.nih.gov/pubmed/20662069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27653 |
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