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The adaptor protein CIKS/Act1 is necessary to induce collagen-induced arthritis pathology and it contributes to collagen-specific antibody production

OBJECTIVE: CIKS/Act1 is an adaptor molecule necessary for signaling by members of the IL-17 cytokine family. Here we aim to determine whether this adaptor is required for collagen-induced arthritis (CIA). If required, CIKS-mediated signaling could be a potential target for therapeutic intervention i...

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Bibliografische gegevens
Hoofdauteurs: Pisitkun, Prapaporn, Claudio, Estefania, Ren, Nina, Wang, Hongshan, Siebenlist, Ulrich
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970656/
https://ncbi.nlm.nih.gov/pubmed/20662069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.27653
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