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Conservation of Functional Asymmetry in the Mammalian MutLα ATPase
The DNA mismatch repair (MMR) protein dimer MutLα is comprised of the MutL homologues MLH1 and PMS2, which each belong to the family of GHL ATPases. These ATPases undergo functionally important conformational changes, including dimerization of the NH(2)-termini associated with ATP binding and hydrol...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2970632/ https://ncbi.nlm.nih.gov/pubmed/20864418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.08.006 |
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