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A Non-Coding RNA Within the Rasgrf1 Locus in Mouse Is Imprinted and Regulated by Its Homologous Chromosome in Trans

BACKGROUND: Rasgrf1 is imprinted in mouse, displaying paternal allele specific expression in neonatal brain. Paternal expression is accompanied by paternal-specific DNA methylation at a differentially methylated domain (DMD) within the locus. The cis-acting elements necessary for Rasgrf1 imprinting...

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Bibliografiske detaljer
Main Authors: Brideau, Chelsea M., Kauppinen, Krista P., Holmes, Rebecca, Soloway, Paul D.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970558/
https://ncbi.nlm.nih.gov/pubmed/21072176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013784
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