A phosphatase activity present in peripheral blood myeloid cells of chronic myelogenous leukemia patients but not normal individuals alters nuclear protein binding to transcriptional enhancers of interferon-inducible genes.

Cytoplasmic protein from peripheral blood myeloid cells of chronic myelogenous leukemia (CML) patients altered the electrophoretic mobility of complexes formed between nuclear proteins and interferon-inducible transcriptional enhancers. Immature myeloid marrow cells (blasts and promyelocytes) have a...

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Bibliographic Details
Main Authors: Seong, D C, Sims, S, Johnson, E, Howard, O M, Reiter, B, Hester, J, Talpaz, M, Kantarjian, H, Deisseroth, A
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC296917/
https://ncbi.nlm.nih.gov/pubmed/2243138
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