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Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells.

Hematopoietic cells from the malignant clone in chronic myelogenous leukemia (CML) maintain and expand a proliferative advantage over normal hematopoietic cells within the bone marrow. This advantage is often ameliorated or reversed in vivo by IFN alpha. Based upon earlier studies suggesting decreas...

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Detalhes bibliográficos
Principais autores: Upadhyaya, G, Guba, S C, Sih, S A, Feinberg, A P, Talpaz, M, Kantarjian, H M, Deisseroth, A B, Emerson, S G
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC295821/
https://ncbi.nlm.nih.gov/pubmed/1721627
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