Interferon-alpha restores the deficient expression of the cytoadhesion molecule lymphocyte function antigen-3 by chronic myelogenous leukemia progenitor cells.

Hematopoietic cells from the malignant clone in chronic myelogenous leukemia (CML) maintain and expand a proliferative advantage over normal hematopoietic cells within the bone marrow. This advantage is often ameliorated or reversed in vivo by IFN alpha. Based upon earlier studies suggesting decreas...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Upadhyaya, G, Guba, S C, Sih, S A, Feinberg, A P, Talpaz, M, Kantarjian, H M, Deisseroth, A B, Emerson, S G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1721627/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115543
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