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Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.

We have studied the effect of glucocorticoids administered in vivo on the activity and synthesis of the cyclooxygenase enzyme (COX) in mice treated with or without concurrent intravenous administration of LPS. Mouse peritoneal macrophages from LPS-treated animals showed a two to three fold increase...

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Pubblicato in:J Clin Invest
Autori principali: Masferrer, J L, Zweifel, B S, Seibert, K, Needleman, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114850
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