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Selective regulation of cellular cyclooxygenase by dexamethasone and endotoxin in mice.

We have studied the effect of glucocorticoids administered in vivo on the activity and synthesis of the cyclooxygenase enzyme (COX) in mice treated with or without concurrent intravenous administration of LPS. Mouse peritoneal macrophages from LPS-treated animals showed a two to three fold increase...

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Библиографические подробности
Опубликовано в::J Clin Invest
Главные авторы: Masferrer, J L, Zweifel, B S, Seibert, K, Needleman, P
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1990
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296874/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2120289/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114850
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