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Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes.

It has been assumed that endogenous synthesis by the platelet precursor cell, the bone marrow megakaryocyte, is the major source of platelet alpha-granule protein. To test this hypothesis, we used mRNA phenotyping to detect in megakaryocytes the presence of mRNA transcripts specific for various prot...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Handagama, P, Rappolee, D A, Werb, Z, Levin, J, Bainton, D F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296872/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2212018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114848
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