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Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules.

Recent data indicate that megakaryocyte/platelet alpha-granule fibrinogen is endocytosed from plasma. Because fibrinogen is the major platelet protein present in high concentrations in alpha-granules, fibrinogen uptake into alpha-granules may occur via specific receptors. In that cells of the megaka...

詳細記述

保存先:
書誌詳細
主要な著者: Handagama, P, Bainton, D F, Jacques, Y, Conn, M T, Lazarus, R A, Shuman, M A
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC330014/
https://ncbi.nlm.nih.gov/pubmed/8423218
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