Platelet alpha-granule fibrinogen, albumin, and immunoglobulin G are not synthesized by rat and mouse megakaryocytes.

It has been assumed that endogenous synthesis by the platelet precursor cell, the bone marrow megakaryocyte, is the major source of platelet alpha-granule protein. To test this hypothesis, we used mRNA phenotyping to detect in megakaryocytes the presence of mRNA transcripts specific for various prot...

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Pubblicato in:	J Clin Invest
Autori principali:	Handagama, P, Rappolee, D A, Werb, Z, Levin, J, Bainton, D F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2212018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114848
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