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Possible role of bacterial siderophores in inflammation. Iron bound to the Pseudomonas siderophore pyochelin can function as a hydroxyl radical catalyst.

Tissue injury has been linked to neutrophil associated hydroxyl radical (.OH) generation, a process that requires an exogenous transition metal catalyst such as iron. In vivo most iron is bound in a noncatalytic form. To obtain iron required for growth, many bacteria secrete iron chelators (sideroph...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Coffman, T J, Cox, C D, Edeker, B L, Britigan, B E
פורמט: Artigo
שפה:Inglês
יצא לאור: 1990
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC296829/
https://ncbi.nlm.nih.gov/pubmed/2170442
תגים: הוספת תג
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