Therapeutic treatment of New Zealand mouse disease by a limited number of anti-idiotypic antibodies conjugated with neocarzinostatin.

-81 and NE-1 idiotypes (Id) of human nephritogenic anti-DNA antibodies are interspecies Id expressed also in NZB/W F1 mice. We tried to manipulate the synthesis of spontaneously occurring anti-DNA antibody using monoclonal anti-Id antibodies (D1E2 and 1F5) conjugated with a cytotoxic agent, neocarzi...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Harata, N, Sasaki, T, Osaki, H, Saito, T, Shibata, S, Muryoi, T, Takai, O, Yoshinaga, K
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1990
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC296791/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2144300/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI114773
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