Therapeutic treatment of New Zealand mouse disease by a limited number of anti-idiotypic antibodies conjugated with neocarzinostatin.

-81 and NE-1 idiotypes (Id) of human nephritogenic anti-DNA antibodies are interspecies Id expressed also in NZB/W F1 mice. We tried to manipulate the synthesis of spontaneously occurring anti-DNA antibody using monoclonal anti-Id antibodies (D1E2 and 1F5) conjugated with a cytotoxic agent, neocarzi...

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Autores principales: Harata, N, Sasaki, T, Osaki, H, Saito, T, Shibata, S, Muryoi, T, Takai, O, Yoshinaga, K
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC296791/
https://ncbi.nlm.nih.gov/pubmed/2144300
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