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Obesity and Leptin Resistance: Distinguishing Cause from Effect

Because leptin reduces food intake and body weight, the coexistence of elevated leptin levels with obesity is widely interpreted as evidence of “leptin resistance.” Indeed, obesity promotes multiple cellular processes that attenuate leptin signaling (referred to here as “cellular leptin resistance”)...

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Autores principales: Myers, Martin G., Leibel, Rudolph L., Seeley, Randy J., Schwartz, Michael W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967652/
https://ncbi.nlm.nih.gov/pubmed/20846876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2010.08.002
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