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Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans

Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of maintaining reduced weight. In our previous studies of in-patient obese subjects, we have shown that leptin repletion following a 10% or greater weight loss reduces many of the metabolic (decreased energy e...

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Библиографические подробности
Главные авторы: Hinkle, William, Cordell, Michael, Leibel, Rudy, Rosenbaum, Michael, Hirsch, Joy
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605420/
https://ncbi.nlm.nih.gov/pubmed/23555620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059114
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