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Effects of Reduced Weight Maintenance and Leptin Repletion on Functional Connectivity of the Hypothalamus in Obese Humans

Treating obesity has proven to be an intractable challenge, in part, due to the difficulty of maintaining reduced weight. In our previous studies of in-patient obese subjects, we have shown that leptin repletion following a 10% or greater weight loss reduces many of the metabolic (decreased energy e...

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Bibliografiske detaljer
Main Authors: Hinkle, William, Cordell, Michael, Leibel, Rudy, Rosenbaum, Michael, Hirsch, Joy
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605420/
https://ncbi.nlm.nih.gov/pubmed/23555620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059114
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