Effect of MTII on food intake and brain c-fos in melanocortin-3, melanocortin-4, and double MC3 and MC4 receptor knockout mice

Mice with genomic knockout of either melanocortin type 3 receptors (MC3R-/-), type 4 receptors (MC4R-/-) or knockout of both (double knockout, DKO) were tested for their anorectic response to the mixed MC3/4R agonist, MTII, injected into the anterior cerebral ventricle. Wild type (WT) mice showed a...

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Main Authors: Rowland, Neil E., Schaub, Jay W., Robertson, Kimberly L., Andreasen, Amy, Haskell-Luevano, Carrie
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967649/
https://ncbi.nlm.nih.gov/pubmed/20800636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2010.08.016
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