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MITRAL VALVULAR INTERSTITIAL CELL RESPONSES TO SUBSTRATE STIFFNESS DEPEND ON AGE AND ANATOMIC REGION

The material properties of heart valves depend on subject age, disease state, and the complex valvular microarchitecture. Furthermore, valvular interstitial cells (VICs) are mechanosensitive, and their synthesis of extracellular matrix not only determines the valve's material properties but als...

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Main Authors: Stephens, Elizabeth H., Durst, Christopher A., West, Jennifer L., Grande-Allen, K. Jane
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967579/
https://ncbi.nlm.nih.gov/pubmed/20624493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.07.001
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