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MITRAL VALVULAR INTERSTITIAL CELL RESPONSES TO SUBSTRATE STIFFNESS DEPEND ON AGE AND ANATOMIC REGION

The material properties of heart valves depend on subject age, disease state, and the complex valvular microarchitecture. Furthermore, valvular interstitial cells (VICs) are mechanosensitive, and their synthesis of extracellular matrix not only determines the valve's material properties but als...

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Detalles Bibliográficos
Main Authors: Stephens, Elizabeth H., Durst, Christopher A., West, Jennifer L., Grande-Allen, K. Jane
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967579/
https://ncbi.nlm.nih.gov/pubmed/20624493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.07.001
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