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MITRAL VALVULAR INTERSTITIAL CELL RESPONSES TO SUBSTRATE STIFFNESS DEPEND ON AGE AND ANATOMIC REGION

The material properties of heart valves depend on subject age, disease state, and the complex valvular microarchitecture. Furthermore, valvular interstitial cells (VICs) are mechanosensitive, and their synthesis of extracellular matrix not only determines the valve's material properties but als...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stephens, Elizabeth H., Durst, Christopher A., West, Jennifer L., Grande-Allen, K. Jane
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967579/
https://ncbi.nlm.nih.gov/pubmed/20624493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2010.07.001
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