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Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cells
The initial requirement for the emergence of CMV-specific CD8(+) T cells is poorly understood. Mice deficient in the cosignaling TNF superfamily member, 4-1BB, surprisingly developed exaggerated early CD8(+) T-cell responses to mouse CMV (MCMV). CD8(+) T cells directed against acute MCMV epitopes we...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
WILEY-VCH Verlag
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967573/ https://ncbi.nlm.nih.gov/pubmed/20722077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200940256 |
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