B7-Mediated Costimulation of CD4 T Cells Constrains Cytomegalovirus Persistence

Cytomegalovirus (CMV) utilizes multiple strategies to modulate immunity and promote lifelong, persistent/latent infection, including suppressing T cell activation pathways. Here we examined the role of B7 costimulatory ligands in establishing immune détente from both the host and virus perspectives....

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Autors principals: Arens, Ramon, Loewendorf, Andrea, Her, Min J., Schneider-Ohrum, Kirsten, Shellam, Geoffrey R., Janssen, Edith, Ware, Carl F., Schoenberger, Stephen P., Benedict, Chris A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Pathogenesis and Immunity
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014178/
https://ncbi.nlm.nih.gov/pubmed/20980516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01839-10
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