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Synergistic epigenetic reactivation of estrogen receptor-α (ERα) by combined green tea polyphenol and histone deacetylase inhibitor in ERα-negative breast cancer cells
BACKGROUND: The status of estrogen receptor-α (ERα) is critical to the clinical prognosis and therapeutic approach in breast cancer. ERα-negative breast cancer is clinically aggressive and has a poor prognosis because of the lack of hormone target-directed therapies. Previous studies have shown that...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2010
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967543/ https://ncbi.nlm.nih.gov/pubmed/20946668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-274 |
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