DNA POLYMERASE β CATALYZED-PCNA INDEPENDENT LONG PATCH BASE EXCISION REPAIR SYNTHESIS: A MECHANISM FOR REPAIR OF OXIDATIVELY DAMAGED DNA ENDS IN POSTMITOTIC BRAIN

Oxidative DNA damage incidental to normal respiratory metabolism poses a particular threat to genomes of highly metabolic-long lived cells. We show that postmitotic brain has capacity to repair oxidatively damaged DNA ends, which are targets of the long patch (LP) base excision repair (BER) sub-path...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Wei, Wei, Englander, Ella W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967482/
https://ncbi.nlm.nih.gov/pubmed/18752643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05644.x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky