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Cyclooxygenase-2 Mediates Anandamide Metabolism in the Mouse Brain

Cyclooxygenase-2 (COX-2) mediates inflammation and contributes to neurodegeneration. Best known for its pathological up-regulation, COX-2 is also constitutively expressed within the brain and mediates synaptic transmission through prostaglandin synthesis. Along with arachidonic acid, COX-2 oxygenate...

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Hlavní autoři: Glaser, Sherrye T., Kaczocha, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967403/
https://ncbi.nlm.nih.gov/pubmed/20702753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168831
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