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Cyclooxygenase-2 Mediates Anandamide Metabolism in the Mouse Brain
Cyclooxygenase-2 (COX-2) mediates inflammation and contributes to neurodegeneration. Best known for its pathological up-regulation, COX-2 is also constitutively expressed within the brain and mediates synaptic transmission through prostaglandin synthesis. Along with arachidonic acid, COX-2 oxygenate...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967403/ https://ncbi.nlm.nih.gov/pubmed/20702753 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168831 |
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