Gold nanoparticle-assisted single base-pair mismatch discrimination on a microfluidic microarray device

Two simple gold nanoparticle (GNP)-based DNA analysis methods using a microfluidic device are presented. In the first method, probe DNA molecules are immobilized on the surface of a self-assembled submonolayer of GNPs. The hybridization efficiency of the target oligonulceotides was improved due to n...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Lin, Li, Paul C. H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Institute of Physics 2010
Konular:
Special Topic: Surface Modification, Wetting, and Biological Interfaces (Guest Editors: John Ralston and Jingfang Zhou)
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967241/
https://ncbi.nlm.nih.gov/pubmed/21045930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3463720
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