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Gold nanoparticle-assisted single base-pair mismatch discrimination on a microfluidic microarray device

Two simple gold nanoparticle (GNP)-based DNA analysis methods using a microfluidic device are presented. In the first method, probe DNA molecules are immobilized on the surface of a self-assembled submonolayer of GNPs. The hybridization efficiency of the target oligonulceotides was improved due to n...

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Detalhes bibliográficos
Main Authors: Wang, Lin, Li, Paul C. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Institute of Physics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2967241/
https://ncbi.nlm.nih.gov/pubmed/21045930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3463720
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