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Gold nanoparticle-assisted single base-pair mismatch discrimination on a microfluidic microarray device
Two simple gold nanoparticle (GNP)-based DNA analysis methods using a microfluidic device are presented. In the first method, probe DNA molecules are immobilized on the surface of a self-assembled submonolayer of GNPs. The hybridization efficiency of the target oligonulceotides was improved due to n...
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| Autores principales: | , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Institute of Physics
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2967241/ https://ncbi.nlm.nih.gov/pubmed/21045930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3463720 |
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