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Effect of gene polymorphisms on the levels of calcineurin inhibitors in Indian renal transplant recipients
The outcome of renal transplantation is improved by cyclosporine and tacrolimus. However, its success is limited by drug-induced nephrotoxicity. Therefore, monitoring their levels is important. These levels are influenced mainly by CYP3A4, CYP3A5 and MDR- 1 genes. These levels also affect target mol...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Medknow Publications
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966981/ https://ncbi.nlm.nih.gov/pubmed/21072155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-4065.70846 |
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