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Effect of gene polymorphisms on the levels of calcineurin inhibitors in Indian renal transplant recipients
The outcome of renal transplantation is improved by cyclosporine and tacrolimus. However, its success is limited by drug-induced nephrotoxicity. Therefore, monitoring their levels is important. These levels are influenced mainly by CYP3A4, CYP3A5 and MDR- 1 genes. These levels also affect target mol...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966981/ https://ncbi.nlm.nih.gov/pubmed/21072155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0971-4065.70846 |
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