Association Between Variants in Calcineurin Inhibitor Pharmacokinetic and Pharmacodynamic Genes and Renal Dysfunction in Adult Heart Transplant Recipients

Background: The goal of the study was to assess the relationship between single nucleotide variants (SNVs) in calcineurin inhibitor (CNI) pharmacokinetic and pharmacodynamic genes and renal dysfunction in adult heart transplant (HTx) recipients. Methods: This retrospective analysis included N = 192...

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Bibliografske podrobnosti
izdano v:Front Genet
Main Authors: Oreschak, Kris, Saba, Laura M., Rafaels, Nicholas, Ambardekar, Amrut V., Deininger, Kimberly M., Page, Robert L., Lindenfeld, JoAnn, Aquilante, Christina L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Genetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047196/
https://ncbi.nlm.nih.gov/pubmed/33868389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.658983
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