Association Between Variants in Calcineurin Inhibitor Pharmacokinetic and Pharmacodynamic Genes and Renal Dysfunction in Adult Heart Transplant Recipients

Background: The goal of the study was to assess the relationship between single nucleotide variants (SNVs) in calcineurin inhibitor (CNI) pharmacokinetic and pharmacodynamic genes and renal dysfunction in adult heart transplant (HTx) recipients. Methods: This retrospective analysis included N = 192...

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Udgivet i:Front Genet
Main Authors: Oreschak, Kris, Saba, Laura M., Rafaels, Nicholas, Ambardekar, Amrut V., Deininger, Kimberly M., Page, Robert L., Lindenfeld, JoAnn, Aquilante, Christina L.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Genetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047196/
https://ncbi.nlm.nih.gov/pubmed/33868389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.658983
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