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Combined CD8(+) and CD4(+) adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

BACKGROUND: Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4(+) T cells has been reported to be associated with sustained protection from adenovirus disease, but epitope specificity...

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Detalhes bibliográficos
Main Authors: Zandvliet, Maarten L., Falkenburg, J.H. Frederik, van Liempt, Ellis, Veltrop-Duits, Louise A., Lankester, Arjan C., Kalpoe, Jayant S., Kester, Michel G.D., van der Steen, Dirk M., van Tol, Maarten J., Willemze, Roel, Guchelaar, Henk-Jan, Schilham, Marco W., Meij, Pauline
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966918/
https://ncbi.nlm.nih.gov/pubmed/20562315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2010.022947
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