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Unexpected Vascular Enrichment of SCO1 over SCO2 in Mammalian Tissues : Implications for Human Mitochondrial Disease
Mammalian SCO1 and SCO2 are evolutionarily-related copper-binding proteins that are required for the assembly of cytochrome c oxidase (COX), a mitochondrial respiratory chain complex, but the exact roles that they play in the assembly process are unclear. Mutations in both SCO1 and SCO2 are associat...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Investigative Pathology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2966810/ https://ncbi.nlm.nih.gov/pubmed/20864674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100229 |
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