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Unexpected Vascular Enrichment of SCO1 over SCO2 in Mammalian Tissues : Implications for Human Mitochondrial Disease

Mammalian SCO1 and SCO2 are evolutionarily-related copper-binding proteins that are required for the assembly of cytochrome c oxidase (COX), a mitochondrial respiratory chain complex, but the exact roles that they play in the assembly process are unclear. Mutations in both SCO1 and SCO2 are associat...

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Detalhes bibliográficos
Main Authors: Brosel, Sonja, Yang, Hua, Tanji, Kurenai, Bonilla, Eduardo, Schon, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966810/
https://ncbi.nlm.nih.gov/pubmed/20864674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100229
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