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Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2
Mutations in SCO2, a protein required for the proper assembly and functioning of cytochrome c oxidase (COX; complex IV of the mitochondrial respiratory chain), cause a fatal infantile cardioencephalomyopathy with COX deficiency. We have generated mice harboring a Sco2 knock-out (KO) allele and a Sco...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2792155/ https://ncbi.nlm.nih.gov/pubmed/19837698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp477 |
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