Analysis of mouse models of cytochrome c oxidase deficiency owing to mutations in Sco2

Mutations in SCO2, a protein required for the proper assembly and functioning of cytochrome c oxidase (COX; complex IV of the mitochondrial respiratory chain), cause a fatal infantile cardioencephalomyopathy with COX deficiency. We have generated mice harboring a Sco2 knock-out (KO) allele and a Sco...

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Hlavní autoři: Yang, Hua, Brosel, Sonja, Acin-Perez, Rebeca, Slavkovich, Vesna, Nishino, Ichizo, Khan, Raffay, Goldberg, Ira J., Graziano, Joseph, Manfredi, Giovanni, Schon, Eric A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792155/
https://ncbi.nlm.nih.gov/pubmed/19837698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp477
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