Development of Sporadic Microsatellite Instability in Colorectal Tumors Involves Hypermethylation at Methylated-In-Tumor Loci in Adenoma

Microsatellite instability (MSI) and genomic hypermethylation of methylated-in-tumor (MINT) loci are both strong prognostic indicators in a subgroup of patients with sporadic colorectal cancer (CRC). The present study was designed to determine whether the methylation of MINT loci during the progress...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: de Maat, Michiel F.G., Narita, Norihiko, Benard, Anne, Yoshimura, Tetsunori, Kuo, Christine, Tollenaar, Rob A.E.M., de Miranda, Noel F.C.C., Turner, Roderick R., van de Velde, Cornelis J.H., Morreau, Hans, Hoon, Dave S.B.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Investigative Pathology 2010
विषय:
Regular Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966793/
https://ncbi.nlm.nih.gov/pubmed/20952593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091103
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