Development of Sporadic Microsatellite Instability in Colorectal Tumors Involves Hypermethylation at Methylated-In-Tumor Loci in Adenoma

Microsatellite instability (MSI) and genomic hypermethylation of methylated-in-tumor (MINT) loci are both strong prognostic indicators in a subgroup of patients with sporadic colorectal cancer (CRC). The present study was designed to determine whether the methylation of MINT loci during the progress...

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Detaylı Bibliyografya
Asıl Yazarlar: de Maat, Michiel F.G., Narita, Norihiko, Benard, Anne, Yoshimura, Tetsunori, Kuo, Christine, Tollenaar, Rob A.E.M., de Miranda, Noel F.C.C., Turner, Roderick R., van de Velde, Cornelis J.H., Morreau, Hans, Hoon, Dave S.B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2010
Konular:
Regular Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966793/
https://ncbi.nlm.nih.gov/pubmed/20952593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.091103
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