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Dendritic cell differentiation with prostaglandin E(2) results in selective attenuation of the extracellular signal-related kinase pathway and decreased interleukin-23 production

The balance between interleukin (IL)-12 and IL-23 production by dendritic cells (DCs) is crucial for the induction of appropriate immune responses. In the present study, we examined the effect of prostaglandin E(2) (PGE(2)) treatment of DCs during differentiation on IL-12 and IL-23 production in res...

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Bibliografiske detaljer
Main Authors: Hayashi, Fumie, Yanagawa, Yoshiki, Onoé, Kazunori, Iwabuchi, Kazuya
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966759/
https://ncbi.nlm.nih.gov/pubmed/20408896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03275.x
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